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Epiretinal gliosis (Makular Pucker)

Epiretinal gliosis (macular pucker, epiretinal membrane) is found in 2% at the age of 50, its prevalence increases to 20% at the age of 70- to 80years.1,2

Various mechanisms can lead to development of epiretinal gliosis: eye operations, inflammatory conditions (uveitis) or retinal vascular occlusions. Most commonly epiretinal membranes develop without a known underlying reason ("idiopathic").Typically epiretinal gliosis affects the centre  of the retina.

Epiretinal gliosis can lead to irregular surface of the retina or tear at the retina. This may lead to reduced visual acuity and   image distortions.

Epiretinal gliosis is diagnosed by ophthalmoscopy, optical coherence tomography (OCT), fluorescein angiography, Amsler Chart or digital measurement with AMD - A Metamorphopsia Detector.



1. Pearlstone, A. D. The incidence of idiopathic preretinal macular gliosis. Ann Ophthalmol 17, 378-380 (1985).

2. Roth, A. M. & Foos, R. Y. Surface wrinkling retinopathy in eyes enucleated at autopsy. Trans Am Acad Ophthalmol Otolaryngol 75, 1047-1058 (1971).

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